Coming Soon: The Magic Stay Healthy and Skinny Forever Pill (TM)
The Obesity Epidemic could soon be over, if the scientists at Sirtris Pharmaceutical are on the money. Their research on the effects of resveratrol have lead to them to synthesize what they have found to be the active component and if this isn’t a potential miracle drug, then I don’t know what is.
The effects of the compound are similar to those of resveratrol, a molecule found in red wine that has previously been shown to extend life span and have health benefits in mice. But SRT1720 is a thousand times more potent than resveratrol, meaning that it could be taken in smaller doses. A person would have to drink hundreds of glasses of wine to get the same health benefits from resveratrol, and, while supplements are available, it is unclear whether they are as effective. “Resveratrol will pretty soon look like ancient technology,” says Sinclair.
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SRT1720, like resveratrol, works by targeting a gene known as sirtuin 1, or SIRT1, which many scientists believe plays a fundamental role in regulating life span. SIRT1 encodes for a class of proteins known as sirtuins, and it is a central controller of mitochondrial activity (mitochondria are the powerhouse energy providers to the cells). “Firing up mitochondria is one of the best treatments against diabetes and obesity because you burn off extra energy instead of storing it,” notes Auwerx.
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Sinclair says that a cousin molecule of SRT1720, which is even more potent, is currently in human trials and will enter clinical studies for the treatment of diseases like type 2 diabetes in 2009. “We could know as early as next year if the same types of benefits we see in mice, we see in humans,” he says.
Read the full article or watch the video overview.
This product is now being marketed as Vivix by the Shaklee Corporation, a potent tonic of resveratrol and a super muscadine grape. Dr. Sinclair is now serving on Shaklee’s medical advisory board, as of August 2008. Vivix HAS been a miracle for me. No more arthritic pain, better sleep, more energy.
[...] SRT1720 is a sirt1 activator and the new hope for a calorie restriction mimicker, which may lead to an increase in human lifespan. read more. Read More|||Scientists at the University of Louis Pasteur in France have taken their studies of the Sirt1 receptor one step further and have now identified a molecule (SRT1720) that when combined with the Sirt1 site tricks the body into thinking it Read More|||SRT1720, which acts through the protein SIRT1, enhances running endurance in exercised mice and protects the animals against weight gain and insulin resistance even when they eat a high-fat diet, the researchers report. Read More|||In mice fed a high fat diet (very similar to the resveratrol study) SRT1720 spared the animals from gaining as much weight (even though they ate the same amount) and becoming insulin resistant. Additionally, the animals fed SRT1720 had Read More|||A new drug called SRT1720 can give you more endurance and make you lose weight. According to researchers, mice who took it could run twice as long, plus they didn%26#39;t gain weight on a high-fat diet. The drug works by tricking your body Read More|||The drug, SRT1720, is reported to mimic the ‘wonder ingredient in red wine’, resveratrol, which is said to ‘fool the body’ that food is scarce and that it needs to live off fat. This research was carried out in mice that were given Read More|||Mice given the new drug, called SRT1720, gorged on high-fat food for four months without gaining weight or developing diabetes, and ran twice as far on a treadmill as their control-group counterparts. Similar drugs are expected to Read More|||The researchers used a new chemical entity, SRT1720, in mouse models to activate the SIRT1 pathway, and assessed its role in obesity, diabetes, ageing and endurance. They found that mice fed a high-fat diet and treated with high doses Read More|||The mice were treated with low doses of the synthetic drug, called SRT1720, showed partial protection against the weight gain after ten weeks of treatment. However, in higher doses, the drug completely prevented weight gain, Read More|||But SRT1720 is a thousand times more potent than resveratrol, meaning that it could be taken in smaller doses. A person would have to drink hundreds of glasses of wine to get the same health benefits from resveratrol, and, Read More [...]
[...] SRT1720 is a sirt1 activator and the new hope for a calorie restriction mimicker, which may lead to an increase in human lifespan. read more. Read More|||Scientists at the University of Louis Pasteur in France have taken their studies of the Sirt1 receptor one step further and have now identified a molecule (SRT1720) that when combined with the Sirt1 site tricks the body into thinking it Read More|||SRT1720, which acts through the protein SIRT1, enhances running endurance in exercised mice and protects the animals against weight gain and insulin resistance even when they eat a high-fat diet, the researchers report. Read More|||In mice fed a high fat diet (very similar to the resveratrol study) SRT1720 spared the animals from gaining as much weight (even though they ate the same amount) and becoming insulin resistant. Additionally, the animals fed SRT1720 had Read More|||A new drug called SRT1720 can give you more endurance and make you lose weight. According to researchers, mice who took it could run twice as long, plus they didn%26#39;t gain weight on a high-fat diet. The drug works by tricking your body Read More|||The drug, SRT1720, is reported to mimic the ‘wonder ingredient in red wine’, resveratrol, which is said to ‘fool the body’ that food is scarce and that it needs to live off fat. This research was carried out in mice that were given Read More|||Mice given the new drug, called SRT1720, gorged on high-fat food for four months without gaining weight or developing diabetes, and ran twice as far on a treadmill as their control-group counterparts. Similar drugs are expected to Read More|||The researchers used a new chemical entity, SRT1720, in mouse models to activate the SIRT1 pathway, and assessed its role in obesity, diabetes, ageing and endurance. They found that mice fed a high-fat diet and treated with high doses Read More|||The mice were treated with low doses of the synthetic drug, called SRT1720, showed partial protection against the weight gain after ten weeks of treatment. However, in higher doses, the drug completely prevented weight gain, Read More|||But SRT1720 is a thousand times more potent than resveratrol, meaning that it could be taken in smaller doses. A person would have to drink hundreds of glasses of wine to get the same health benefits from resveratrol, and, Read More [...]
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… Wow. Can we have an Oryx and Crake reading club?
I’m more partial to drinking hundreds of glasses of wine though.
way to be a buzz kill science.
Martha,
Are you sure that Dr sinclair’s SRT1720 is the form of resveratrol that Shaklee uses?
Mike
Actually I’d like to pose this question to anyone who has a source that shows that Dr sinclair’s SRT1720 is the form of resveratrol that Shaklee uses in Vivix.
Thanks
Mike